publication . Article . Other literature type . 2009

IGF-I during primiparous pregnancy and maternal risk of breast cancer

Chen, Tianhui; Lukanova, Annekatrin; Grankvist, Kjell; Zeleniuch-Jacquotte, Anne; Wulff, Marianne; Johansson, Robert; Schock, Helena; Lenner, Per; Hallmans, Goran; Wadell, Goran; ...
Open Access English
  • Published: 02 Sep 2009
  • Publisher: Springer Verlag
Abstract
International audience; Previously, we reported that insulin-like growth factor (IGF)-I during early pregnancy is positively associated with maternal risk of breast cancer. To further explore this association, we designed a new study limited to women who donated a blood sample during their first pregnancy ending with childbirth. A case–control study was nested within the Northern Sweden Maternity Cohort in which repository since 1975, serum specimens remaining after early pregnancy screening for infectious diseases had been preserved. Study subjects were selected among women who donated a blood sample during the full-term pregnancy that led to the birth of their...
Subjects
free text keywords: Pregnancy, Breast cancer, Nested case–control study, Insulin-like growth factor (IGF)-I, Article
Funded by
NIH| Pregnancy Hormones and Risk of Maternal Breast Cancer
Project
  • Funder: National Institutes of Health (NIH)
  • Project Code: 5R01CA114329-02
  • Funding stream: NATIONAL CANCER INSTITUTE

Table 2. ORs and 95% CI by tertiles of IGF-I concentrations*, # 1 2 3

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publication . Article . Other literature type . 2009

IGF-I during primiparous pregnancy and maternal risk of breast cancer

Chen, Tianhui; Lukanova, Annekatrin; Grankvist, Kjell; Zeleniuch-Jacquotte, Anne; Wulff, Marianne; Johansson, Robert; Schock, Helena; Lenner, Per; Hallmans, Goran; Wadell, Goran; ...