Comparison of statistical models to estimate parasite growth rate in the induced blood stage malaria model

Article English OPEN
Wockner, Leesa F.; Hoffmann, Isabell; O’Rourke, Peter; McCarthy, James S.; Marquart, Louise;
  • Publisher: BMC
  • Journal: Malaria Journal, volume 16 (issn: 1475-2875, eissn: 1475-2875)
  • Publisher copyright policies & self-archiving
  • Identifiers: doi: 10.1186/s12936-017-1999-1, pmc: PMC5574106
  • Subject: Clinical trial | RC955-962 | RC109-216 | Controlled human malaria infection | Fixed intercept regression | Induced blood stage malaria | Infectious and parasitic diseases | Statistical modelling | Arctic medicine. Tropical medicine | Methodology | Parasite growth rate

Background The efficacy of vaccines aimed at inhibiting the growth of malaria parasites in the blood can be assessed by comparing the growth rate of parasitaemia in the blood of subjects treated with a test vaccine compared to controls. In studies using induced blood st... View more
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