Use of Arctium lappa Extract Against Acetaminophen-Induced Hepatotoxicity in Rats

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El-Kott, Attalla Farag; Bin-Meferij, Mashael Mohammed;
  • Publisher: Elsevier BV
  • Journal: Current Therapeutic Research, volume 77, pages 73-78 (issn: 0011-393X, eissn: 1879-0313)
  • Publisher copyright policies & self-archiving
  • Identifiers: doi: 10.1016/j.curtheres.2015.05.001, pmc: PMC4564434
  • Subject: lipid peroxidation | acetaminophen | RM1-950 | comet assay | Therapeutics. Pharmacology | hepatotoxicity | Pharmacology | Original Research | Arctium lappa | Pharmacology (medical)
    mesheuropmc: digestive system | digestive system diseases | stomatognathic diseases | digestive, oral, and skin physiology | organic chemicals

Background: Severe destructive hepatic injuries can be induced by acetaminophen overdose and may lead to acute hepatic failure. Objective: To investigate the ameliorative effects of Arctium lappa root extract on acetaminophen-induced hepatotoxicity. Methods: Rats ... View more
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