The small heat shock protein αA-crystallin is expressed in pancreas and acts as a negative regulator of carcinogenesis

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Deng , Mi; Chen , Pei-Chao; Xie , Sisi; Zhao , Junqiong; Gong , Lili; Liu , Jinping; Zhang , Lan; Sun , Shuming; Liu , Jiao; Ma , Haili; Batra , Surinder; Li , David Wan-Cheng;
(2010)
  • Publisher: Elsevier BV
  • Journal: Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease,volume 1,802,issue 7-8,pages621-631 (issn: 0925-4439)
  • Publisher copyright policies & self-archiving
  • Related identifiers: doi: 10.1016/j.bbadis.2010.04.004
  • Subject: αA | Molecular Biology | Pancreatic Cancer | Pancreas | Small heat shock protein | Cell migration | Molecular Medicine | TGFβ | Smad2/3/5 | AP-1
    mesheuropmc: eye diseases | sense organs

International audience; The small heat shock protein αA-crystallin is a structural protein in the ocular lens. In addition, recent studies have also revealed that it is a molecular chaperone, an autokinase and a strong anti-apoptotic regulator. Besides its lenticular di... View more
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