Development of Solid SEDDS, IV: Effect of Adsorbed Lipid and Surfactant on Tableting Properties and Surface Structures of Different Silicates

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Gumaste, Suhas G.; Pawlak, Sara A.; Dalrymple, Damon M.; Nider, Charles J.; Trombetta, Louis D.; Serajuddin, Abu T. M.;
  • Publisher: Springer US
  • Journal: Pharmaceutical Research,volume 30,issue 12,pages3,170-3,185 (issn: 0724-8741, eissn: 1573-904X)
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  • Related identifiers: doi: 10.1007/s11095-013-1114-4, pmc: PMC3841658
  • Subject: Biotechnology | adsorption | SEM images | Pharmaceutical Science | lipid | tablet | silicate | tabletability | Organic Chemistry | Pharmacology | Molecular Medicine | comparative evaluation | Neusilin® US2 | Research Paper | Pharmacology (medical) | surfactant

ABSTRACT Purpose To compare six commonly available silicates for their suitability to develop tablets by adsorbing components of liquid lipid-based drug delivery systems. Methods The tabletability of Aerosil® 200, Sipernat® 22, Sylysia® 350, Zeopharm® 600, Neusilin® US2... View more
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