Histological staining methods preparatory to laser capture microdissection significantly affect the integrity of the cellular RNA

Article English OPEN
Li Ming-Chung; Shih Joanna H; Owens James D; Wang Hongyang; Bonner Robert F; Mushinski J Frederic;

<p>Abstract</p> <p>Background</p> <p>Gene expression profiling by microarray analysis of cells enriched by laser capture microdissection (LCM) faces several technical challenges. Frozen sections yield higher quality RNA than paraffin-imbedded sections, but even with fro... View more
Share - Bookmark