Structural model of FeoB, the iron transporter from Pseudomonas aeruginosa, predicts a cysteine lined, GTP-gated pore

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Seyedmohammad, Saeed; Alveal, Natalia; Marriott, Robert AJ; Goetze, Tom A; Edwardson, John; Barrera, Nelson P; Venter, Henrietta;
(2016)

Iron is essential for the survival and virulence of pathogenic bacteria. The FeoB transporter allows the bacterial cell to acquire ferrous iron from its environment, making it an excellent drug target in intractable pathogens. The protein consists of an N-terminal GTP b... View more
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