A live-attenuated chimeric porcine circovirus type 2 (PCV2) vaccine is transmitted to contact pigs but is not upregulated by concurrent infection with porcine parvovirus (PPV) and porcine reproductive and respiratory syndrome virus (PRRSV) and is efficacious in a PCV2b-PRRSV-PPV challenge model

Article, Other literature type English OPEN
Opriessnig, T.; Shen, H. G.; Pal, N.; Ramamoorthy, S.; Huang, Y. W.; Lager, K. M.; Beach, N. M.; Halbur, P. G.; Meng, X. J.;
  • Publisher: American Society for Microbiology
  • Related identifiers: doi: 10.1128/CVI.05057-11, pmc: PMC3147358
  • Subject: Swine | Circovirus | Viral Vaccines | Parvovirus, Porcine | Vaccine Research | Porcine respiratory and reproductive syndrome virus | Animals | Swine Diseases | Circoviridae Infections | Vaccines, Attenuated
    mesheuropmc: virus diseases | animal diseases

The live chimeric porcine circovirus type 2 (PCV2) vaccine with the capsid gene of the emerging subtype 2b cloned in the genomic backbone of the nonpathogenic PCV1 is attenuated in vivo and induces protective immunity against PCV2. To further determine the safety and ef... View more
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