Inclusion complex of the antiviral drug acyclovir with cyclodextrin in aqueous solution and in solid phase

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Carlos von Plessing Rossel; Jacqueline Sepúlveda Carreño; Mario Rodríguez-Baeza; Joel Bernabé Alderete;
(2000)

Complexation between acyclovir (ACV), an antiviral drug used for the treatment of herpes simplex virus infection, and beta-cyclodextrin (beta-CD) was studied in solution and in solid states. Complexation in solution was evaluated using solubility studies and nuclear mag... View more