SH2 domains: modulators of nonreceptor tyrosine kinase activity

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Filippakopoulos, Panagis; Müller, Susanne; Knapp, Stefan;

(2009)

Publisher: Elsevier BV

Journal: Current Opinion in Structural Biology, volume 19, issue 6, pages 643-649 (issn: 0959-440X, eissn: 1879-033X)

Publisher copyright policies & self-archiving

Identifiers: doi: 10.1016/j.sbi.2009.10.001, pmc: PMC2791838
Subject: Molecular Biology | Structural Biology | Article
mesheuropmc: animal structures

The Src homology 2 (SH2) domain is a sequence-specific phosphotyrosine-binding module present in many signaling molecules. In cytoplasmic tyrosine kinases, the SH2 domain is located N-terminally to the catalytic kinase domain (SH1) where it mediates cellular localizatio... View more

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UNIVERSITY OF OXFORD	90%
Structural Genomics Consortium ( SGC ) United Kingdom Website url: http://www.thesgc.org/	90%
University of Oxford	90%
University of Oxford ( University of Oxford ) United Kingdom Website url: http://www.ox.ac.uk/	90%
University Of Oxford	90%

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