publication . Article . 2017

Fish Scale Collagen Peptides Protect against CoCl2/TNF-α-Induced Cytotoxicity and Inflammation via Inhibition of ROS, MAPK, and NF-κB Pathways in HaCaT Cells

Subhan, Fazli; Kang, Hae Yeong; Lim, Yeseon; Ikram, Muhammad; Baek, Sun-Yong; Jin, Songwan; Jeong, Young Hun; Kwak, Jong Young; Yoon, Sik;
Open Access English
  • Published: 01 Jun 2017 Journal: Oxidative Medicine and Cellular Longevity, volume 2,017 (issn: 1942-0900, eissn: 1942-0994, Copyright policy)
  • Publisher: Hindawi
Abstract
Skin diseases associated with inflammation or oxidative stress represent the most common problem in dermatology. The present study demonstrates that fish scale collagen peptides (FSCP) protect against CoCl2-induced cytotoxicity and TNF-alpha-induced inflammatory responses in human HaCaT keratinocyte cells. Our study is the first to report that FSCP increase cell viability and ameliorate oxidative injury in HaCaT cells through mechanisms mediated by the downregulation of key proinflammatory cytokines, namely, TNF-alpha, IL-1 beta, IL-8, and iNOS. FSCP also prevent cell apoptosis by repressing Bax expression, caspase-3 activity, and cytochrome c release and by upr...
Subjects
free text keywords: Cytology, Research Article, QH573-671, Article Subject
63 references, page 1 of 5

Coman, G., Blickenstaff, N. R., Maibach, H. I.. Skin and the environment. Reviews on Environmental Health . 2014; 29 (3): p. 143 [PubMed] [] [DOI]

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Kim, J. H., Jin, Z. W., Murakami, G., Cho, B. H.. Characterization of mesenchymal cells beneath cornification of the fetal epithelium and epidermis at the face: an immunohistochemical study using human fetal specimens. Anatomy and Cell Biology . 2016; 49 (1): 50-60 [OpenAIRE] [PubMed] [] [DOI]

Bickers, D. R., Athar, M.. Oxidative stress in the pathogenesis of skin disease. The Journal of Investigative Dermatology . 2006; 126 (12): 2565-2575 [OpenAIRE] [PubMed] [] [DOI]

Narendhirakannan, R. T., Hannah, M. A.. Oxidative stress and skin cancer: an overview. Indian Journal of Clinical Biochemistry . 2013; 28 (2): 110-115 [OpenAIRE] [PubMed] [] [DOI]

Kim, M. Y., Lim, Y. Y., Kim, H. M., Park, Y. M., Kang, H., Kim, B. J.. Synergistic inhibition of tumor necrosis factor-alpha-stimulated pro-inflammatory cytokine expression in HaCaT cells by a combination of rapamycin and mycophenolic acid. Annals of Dermatology . 2015; 27 (1): 32-39 [OpenAIRE] [PubMed] [] [DOI]

Kobielak, A., Boddupally, K.. Junctions and inflammation in the skin. Cell Communication & Adhesion . 2014; 21 (3): 141-147 [PubMed] [] [DOI]

Choi, Y. H., Yan, G. H., Chai, O. H., Song, C. H.. Inhibitory effects of curcumin on passive cutaneous anaphylactoid response and compound 48/80-induced mast cell activation. Anatomy and Cell Biology . 2010; 43 (1): 36-43 [OpenAIRE] [PubMed] [DOI]

Kumari, S., Pasparakis, M.. Epithelial cell death and inflammation in skin. Current Topics in Microbiology and Immunology . 2015; 2015: 1-17 [PubMed] [DOI]

Mustoe, T. A., O’Shaughnessy, K., Kloeters, O.. Chronic wound pathogenesis and current treatment strategies: a unifying hypothesis. Plastic and Reconstructive Surgery . 2006; 117 (7): 35S-41S [PubMed] [] [DOI]

Yang, C., Ling, H., Zhang, M.. Oxidative stress mediates chemical hypoxia-induced injury and inflammation by activating NF-κb-COX-2 pathway in HaCaT cells. Molecules and Cells . 2011; 6 (6): 531-538 [OpenAIRE] [PubMed] [] [DOI]

Watanabe, K., Kawamori, T., Nakatsugi, S., Wakabayashi, K.. COX-2 and iNOS, good targets for chemoprevention of colon cancer. Biofactors . 2002; 12 (1–4): 129-133 [PubMed] [DOI]

Wang, J. K., Xiong, G. M., Luo, B.. Surface modification of PVDF using non-mammalian sources of collagen for enhancement of endothelial cell functionality. Journal of Materials Science. Materials in Medicine . 2016; 27 (3): p. 45 [OpenAIRE] [PubMed] [] [DOI]

Liu, C., Xue, Y., Sun, J.. Hydrolyzed fish collagen inhibits inflammatory cytokines secretion in lipopolysaccharide-induced HUVECs. Advances in Materials Research . 2014; 1025-1026: 570-573 [] [DOI]

Yamamoto, K., Igawa, K., Sugimoto, K.. Biological safety of fish (tilapia) collagen. BioMed Research International . 2014; 2014: 9 [OpenAIRE] [] [] [PubMed] [DOI]

63 references, page 1 of 5
Abstract
Skin diseases associated with inflammation or oxidative stress represent the most common problem in dermatology. The present study demonstrates that fish scale collagen peptides (FSCP) protect against CoCl2-induced cytotoxicity and TNF-alpha-induced inflammatory responses in human HaCaT keratinocyte cells. Our study is the first to report that FSCP increase cell viability and ameliorate oxidative injury in HaCaT cells through mechanisms mediated by the downregulation of key proinflammatory cytokines, namely, TNF-alpha, IL-1 beta, IL-8, and iNOS. FSCP also prevent cell apoptosis by repressing Bax expression, caspase-3 activity, and cytochrome c release and by upr...
Subjects
free text keywords: Cytology, Research Article, QH573-671, Article Subject
63 references, page 1 of 5

Coman, G., Blickenstaff, N. R., Maibach, H. I.. Skin and the environment. Reviews on Environmental Health . 2014; 29 (3): p. 143 [PubMed] [] [DOI]

Bos, J. D., Kapsenberg, M. L.. The skin immune system: progress in cutaneous biology. Immunology Today . 1993; 14 (2): 75-78 [OpenAIRE] [PubMed] [] [DOI]

Kim, J. H., Jin, Z. W., Murakami, G., Cho, B. H.. Characterization of mesenchymal cells beneath cornification of the fetal epithelium and epidermis at the face: an immunohistochemical study using human fetal specimens. Anatomy and Cell Biology . 2016; 49 (1): 50-60 [OpenAIRE] [PubMed] [] [DOI]

Bickers, D. R., Athar, M.. Oxidative stress in the pathogenesis of skin disease. The Journal of Investigative Dermatology . 2006; 126 (12): 2565-2575 [OpenAIRE] [PubMed] [] [DOI]

Narendhirakannan, R. T., Hannah, M. A.. Oxidative stress and skin cancer: an overview. Indian Journal of Clinical Biochemistry . 2013; 28 (2): 110-115 [OpenAIRE] [PubMed] [] [DOI]

Kim, M. Y., Lim, Y. Y., Kim, H. M., Park, Y. M., Kang, H., Kim, B. J.. Synergistic inhibition of tumor necrosis factor-alpha-stimulated pro-inflammatory cytokine expression in HaCaT cells by a combination of rapamycin and mycophenolic acid. Annals of Dermatology . 2015; 27 (1): 32-39 [OpenAIRE] [PubMed] [] [DOI]

Kobielak, A., Boddupally, K.. Junctions and inflammation in the skin. Cell Communication & Adhesion . 2014; 21 (3): 141-147 [PubMed] [] [DOI]

Choi, Y. H., Yan, G. H., Chai, O. H., Song, C. H.. Inhibitory effects of curcumin on passive cutaneous anaphylactoid response and compound 48/80-induced mast cell activation. Anatomy and Cell Biology . 2010; 43 (1): 36-43 [OpenAIRE] [PubMed] [DOI]

Kumari, S., Pasparakis, M.. Epithelial cell death and inflammation in skin. Current Topics in Microbiology and Immunology . 2015; 2015: 1-17 [PubMed] [DOI]

Mustoe, T. A., O’Shaughnessy, K., Kloeters, O.. Chronic wound pathogenesis and current treatment strategies: a unifying hypothesis. Plastic and Reconstructive Surgery . 2006; 117 (7): 35S-41S [PubMed] [] [DOI]

Yang, C., Ling, H., Zhang, M.. Oxidative stress mediates chemical hypoxia-induced injury and inflammation by activating NF-κb-COX-2 pathway in HaCaT cells. Molecules and Cells . 2011; 6 (6): 531-538 [OpenAIRE] [PubMed] [] [DOI]

Watanabe, K., Kawamori, T., Nakatsugi, S., Wakabayashi, K.. COX-2 and iNOS, good targets for chemoprevention of colon cancer. Biofactors . 2002; 12 (1–4): 129-133 [PubMed] [DOI]

Wang, J. K., Xiong, G. M., Luo, B.. Surface modification of PVDF using non-mammalian sources of collagen for enhancement of endothelial cell functionality. Journal of Materials Science. Materials in Medicine . 2016; 27 (3): p. 45 [OpenAIRE] [PubMed] [] [DOI]

Liu, C., Xue, Y., Sun, J.. Hydrolyzed fish collagen inhibits inflammatory cytokines secretion in lipopolysaccharide-induced HUVECs. Advances in Materials Research . 2014; 1025-1026: 570-573 [] [DOI]

Yamamoto, K., Igawa, K., Sugimoto, K.. Biological safety of fish (tilapia) collagen. BioMed Research International . 2014; 2014: 9 [OpenAIRE] [] [] [PubMed] [DOI]

63 references, page 1 of 5
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publication . Article . 2017

Fish Scale Collagen Peptides Protect against CoCl2/TNF-α-Induced Cytotoxicity and Inflammation via Inhibition of ROS, MAPK, and NF-κB Pathways in HaCaT Cells

Subhan, Fazli; Kang, Hae Yeong; Lim, Yeseon; Ikram, Muhammad; Baek, Sun-Yong; Jin, Songwan; Jeong, Young Hun; Kwak, Jong Young; Yoon, Sik;