COMPUTATIONAL ENZYME DESIGN APPROACHES WITH SIGNIFICANT BIOLOGICAL OUTCOMES: PROGRESS AND CHALLENGES

Article English OPEN
Li, Xiaoman; Zhang, Ziding; Song, Jiangning;
(2012)
  • Publisher: Elsevier BV
  • Journal: Computational and Structural Biotechnology Journal,volume 2,issue 3 (issn: 2001-0370, eissn: 2001-0370)
  • Related identifiers: doi: 10.5936/csbj.201209007, pmc: PMC3962085
  • Subject: Biotechnology | Mini Review | TP248.13-248.65

Enzymes are powerful biocatalysts, however, so far there is still a large gap between the number of enzyme-based practical applications and that of naturally occurring enzymes. Multiple experimental approaches have been applied to generate nearly all possible mutations ... View more
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