Ontogeny of human IgE‐expressing B cells and plasma cells
Hobson, P. S.
Chang, T. W.
McDonnell, J. M.
Sutton, B. J.
Fear, D. J.
Gould, H. J.
- Publisher: John Wiley and Sons Inc.
(issn: 0105-4538, eissn: 1398-9995)
Experimental Allergy and Immunology | Original Article | germinal centre | ORIGINAL ARTICLES | IgE class switching | allergy | human B cells | plasma cell
<p>BACKGROUND: IgE-expressing (IgE<sup>+</sup>) plasma cells (PCs) provide a continuous source of allergen specific IgE that is central to allergic responses. The extreme sparsity of IgE<sup>+</sup> cells in vivo has confined their study almost entirely to mouse models....