Genomic and Metagenomic Analysis of Diversity-Generating Retroelements Associated with Treponema denticola

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Nimkulrat, Sutichot; Lee, Heewook; Doak, Thomas G.; Ye, Yuzhen;
  • Publisher: Frontiers Media S.A.
  • Journal: Frontiers in Microbiology,volume 7 (issn: 1664-302X, eissn: 1664-302X)
  • Related identifiers: pmc: PMC4891356, doi: 10.3389/fmicb.2016.00852/full, doi: 10.3389/fmicb.2016.00852
  • Subject: human microbiome | reverse transcriptase | Treponema denticola | Microbiology | Original Research | template region (TR) | QR1-502 | template region | diversity-generating retroelements
    mesheuropmc: stomatognathic diseases

Diversity-generating retroelements (DGRs) are genetic cassettes that can produce massive protein sequence variation in prokaryotes. Presumably DGRs confer selective advantages to their hosts (bacteria or viruses) by generating variants of target genes—typically resultin... View more
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