Effects of Genetic Mutations and Chemical Exposures on Caenorhabditis elegans Feeding: Evaluation of a Novel, High-Throughput Screening Assay

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Boyd, Windy A. ; McBride, Sandra J. ; Freedman, Jonathan H. (2007)
  • Publisher: Public Library of Science
  • Journal: PLoS ONE, volume 2, issue 12 (issn: 1932-6203, eissn: 1932-6203)
  • Related identifiers: doi: 10.1371/journal.pone.0001259, pmc: PMC2092392
  • Subject: Q | R | Biotechnology | Research Article | Public Health and Epidemiology/Environmental Health | Science | Medicine | Pharmacology/Adverse Reactions

Background Government agencies have defined a need to reduce, refine or replace current mammalian-based bioassays with testing methods that use alternative species. Invertebrate species, such as Caenorhabditis elegans, provide an attractive option because of their short... View more
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