Prenatal anxiety, maternal stroking in infancy, and symptoms of emotional and behavioral disorders at 3.5 years

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Pickles, Andrew; Sharp, Helen; Hellier, Jennifer; Hill, Jonathan;
  • Publisher: Springer Berlin Heidelberg
  • Journal: volume 26,issue 3,pages325-334issn: 1018-8827, eissn: 1435-165X
  • Publisher copyright policies & self-archiving
  • Related identifiers: doi: 10.1007/s00787-016-0886-6, pmc: PMC5323471
  • Subject: Developmental and Educational Psychology | Emotional | Philosophy | Epigenetics | Psychiatry and Mental health | Prenatal anxiety | Pediatrics, Perinatology, and Child Health | /dk/atira/pure/subjectarea/asjc/2700/2738 | Fetal programing | /dk/atira/pure/subjectarea/asjc/3200/3204 | Original Contribution | /dk/atira/pure/subjectarea/asjc/1200/1211 | Behavioral disorders | Tactile stimulation | /dk/atira/pure/subjectarea/asjc/2700/2735

Animal findings of long-term effects of maternal behaviors mediated via altered GR gene expression will, if translated into humans, have far reaching implications for our understanding of child and adolescent psychopathology. We have previously shown that mothers’ self-... View more
  • References (41)
    41 references, page 1 of 5

    1. Meaney MJ, Szyf M, Seckl JR (2007) Epigenetic mechanisms of perinatal programming of hypothalamic-pituitary-adrenal function and health. Trends Mol Med. 13(7):269-277

    2. Meaney MJ (2010) Epigenetics and the biological definition of gene x environment interactions. Child Dev 81(1):41-79 Epub 2010/03/25

    3. Hellstrom IC, Dhir SK, Diorio JC, Meaney MJ (2012) Maternal licking regulates hippocampal glucocorticoid receptor transcription through a thyroid hormone-serotonin-NGFIA signalling cascade. Philos Trans R Soc Lond B Biol Sci 367(1601):2495-2510

    4. Barker ED, Jaffee SR, Uher R, Maughan B (2011) The contribution of prenatal and postnatal maternal anxiety and depression to child maladjustment. Depress Anxiety 28(8):696-702 Epub 2011/07/20

    5. O'Connor TG, Heron J, Golding J, Glover V (2003) Maternal antenatal anxiety and behavioural/emotional problems in children: a test of a programming hypothesis. J Child Psychol Psychiatry 44(7):1025-1036

    6. Barker ED, Maughan B (2009) Differentiating early-onset persistent versus childhood-limited conduct problem youth. Am J Psychiatry 166(8):900-908 Epub 2009/07/03

    7. Blair MM, Glynn LM, Sandman CA, Davis EP (2011) Prenatal maternal anxiety and early childhood temperament. Stress Int J Biol Stress 14(6):644-651

    8. Buss C, Davis EP, Hobel CJ, Sandman CA (2011) Maternal pregnancy-specific anxiety is associated with child executive function at 6-9 years age. Stress. 14(6):665-676 Epub 2011/10/15

    9. Weinstock M (2007) Gender differences in the effects of prenatal stress on brain development and behaviour. Neurochem Res 32(10):1730-1740

    10. Weinstock M (2011) Sex-dependent changes induced by prenatal stress in cortical and hippocampal morphology and behaviour in rats: an update. Stress. 14(6):604-613 (Epub 2011/07/28)

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