A Damage Sensor Associated with the Cuticle Coordinates Three Core Environmental Stress Responses in Caenorhabditis elegans

Article English OPEN
Dodd, William; Tang, Lanlan; Lone, Jean-Christophe; Wimberly, Keon; Wu, Cheng-Wei; Consalvo, Claudia; Wright, Joni; Pujol, Nathalie; Choe, Keith;

Extracellular matrix barriers and inducible cytoprotective genes form successive lines of defense against chemical and microbial environmental stressors. The barrier in nematodes is a collagenous extracellular matrix called the cuticle. In Caenorhabditis elegans, disrup... View more