Prion protein (PrP) gene-knockout cell lines: insight into functions of the PrP

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Akikazu eSakudo; Takashi eOnodera;

Elucidation of prion protein (PrP) functions is crucial to fully understand prion diseases. A major approach to studying PrP functions is the use of PrP gene-knockout (Prnp-/-) mice. So far, six types of Prnp-/- mice have been generated, demonstrating the promiscuous fu... View more
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