Sex-Specific Protection of Osteoarthritis by Deleting Cartilage Acid Protein 1.

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Ge, Xianpeng; Ritter, Susan Y.; Tsang, Kelly; Shi, Ruirui; Takei, Kohtaro; Aliprantis, Antonios O.;
(2016)
  • Publisher: Public Library of Science (PLoS)
  • Journal: PLoS ONE,volume 11,issue 7 (issn: 1932-6203, eissn: 1932-6203)
  • Publisher copyright policies & self-archiving
  • Related identifiers: doi: 10.1371/journal.pone.0159157., doi: 10.1371/journal.pone.0159157, pmc: PMC4945026
  • Subject: Chondrocytes | Research Article | Anatomy | Osteoarthritis | Staining | Rheumatology | Biomechanics | Gait Analysis | Fibroblasts | Cytoplasmic Staining | Safranin Staining | Biological Tissue | Histology | Connective Tissue | Articular Cartilage | Cellular Types | Biological Locomotion | Biology and Life Sciences | Cartilage | Research and Analysis Methods | Physiology | Animal Cells | Medicine | Connective Tissue Cells | Specimen Preparation and Treatment | Q | R | Cell Biology | Arthritis | Science | Medicine and Health Sciences

Cartilage acidic protein 1 (CRTAC1) was recently identified as an elevated protein in the synovial fluid of patients with osteoarthritis (OA) by a proteomic analysis. This gene is also upregulated in both human and mouse OA by transcriptomic analysis. The objective of t... View more
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