Host Genetics: Fine-Tuning Innate Signaling

Article, Other literature type English OPEN
Fellay, Jacques ; Goldstein, David B. (2007)
  • Publisher: Elsevier BV
  • Journal: Current Biology, volume 17, issue 13, pages R516-R518 (issn: 0960-9822)
  • Related identifiers: doi: 10.1016/j.cub.2007.04.052
  • Subject: Agricultural and Biological Sciences(all) | Biochemistry, Genetics and Molecular Biology(all) | Article

A polymorphism modulating innate immunity signal transduction has recently been shown to influence human susceptibility to many different infections, providing one more indication of the potential of host genetics to reveal physiological pathways and mechanisms that influence resistance to infectious diseases.
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