Genome-wide association study in east Asians identifies novel susceptibility loci for breast cancer.

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Jirong Long ; Qiuyin Cai ; Hyuna Sung ; Jiajun Shi ; Ben Zhang ; Ji-Yeob Choi ; Wanqing Wen ; Ryan J Delahanty ; Wei Lu ; Yu-Tang Gao ; Hongbing Shen ; Sue K Park ; Kexin Chen ; Chen-Yang Shen ; Zefang Ren ; Christopher A Haiman ; Keitaro Matsuo ; Mi Kyung Kim ; Ui Soon Khoo ; Motoki Iwasaki ; Ying Zheng ; Yong-Bing Xiang ; Kai Gu ; Nathaniel Rothman ; Wenjing Wang ; Zhibin Hu ; Yao Liu ; Keun-Young Yoo ; Dong-Young Noh ; Bok-Ghee Han ... view all 52 authors
  • Publisher: Public Library of Science (PLoS)
  • Journal: PLoS Genetics, volume 8, issue 2 (issn: 1553-7390, eissn: 1553-7404)
  • Related identifiers: doi: 10.1371/journal.pgen.1002532, pmc: PMC3285588
  • Subject: Global Health | Research Article | Asian | Breast cancer | Medicine | Oncology | Epidemiology | Chinese | QH426-470 | Genetics | Cancer staging | Clinical Genetics | Women's Health | Cancer risk | Public Health

Genetic factors play an important role in the etiology of both sporadic and familial breast cancer. We aimed to discover novel genetic susceptibility loci for breast cancer. We conducted a four-stage genome-wide association study (GWAS) in 19,091 cases and 20,606 contro... View more