Detection of haplotypes associated with prenatal death in dairy cattle and identification of deleterious mutations in GART, SHBG and SLC37A2

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Fritz, Sebastien ; Capitan, Aurelien ; Djari, Anis ; Rodriguez, Sabrina ; Barbat, Anne ; Baur, Aurélia ; Grohs, Cecile ; Weiss, Bernard ; Boussaha, Mekki ; Esquerre, Diane ; Klopp, Christophe ; Rocha, Dominique (2013)
  • Publisher: Public Library of Science (PLoS)
  • Journal: PLoS ONE, volume 8, issue 6 (issn: 1932-6203, eissn: 1932-6203)
  • Related identifiers: pmc: PMC3676330, doi: 10.1371/journal.pone.0065550
  • Subject: Animal Breeding | Research Article | mortalité embryonnaire | fertilité animale | Agriculture | Evolutionary Biology | Animal Types | cattle;fertility;gart gene;shbg gene;slc37a2 gene;embryo mortality | Large Animals | Population Genetics | Biology | Female Subfertility | Veterinary Science | Medicine | Q | R | Population Biology | Animal Genetics | Genetic Testing | Clinical Genetics | Obstetrics and Gynecology | Science | bovin | gène gart | gène shbg | Animal Management | Genetic Polymorphism | Autosomal Recessive | Animal Production

The regular decrease of female fertility over time is a major concern in modern dairy cattle industry. Only half of this decrease is explained by indirect response to selection on milk production, suggesting the existence of other factors such as embryonic lethal geneti... View more
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