Thy-1-mediated cell-cell contact induces astrocyte migration through the engagement of alpha v beta(3) integrin and syndecan-4

Article, Other literature type English OPEN
Kong, Milene; Munoz, Nicolas; Valdivia, Alejandra; Alvarez, Alvaro; Herrera-Molina, Rodrigo; Cardenas, Areli; Schneider, Pascal; Burridge, Keith; Quest, Andrew F. G.; Leyton, Lisette;
  • Journal: volume 1,833,issue 6,pages1,409-1,420issn: 0167-4889
  • Related identifiers: doi: 10.1016/j.bbamcr.2013.02.013, pmc: PMC3726046
  • Subject: Molecular Biology | Cell Biology | Thy-1; Integrin; Syndecan-4; Neuron-astrocyte interaction; Cell migration | Article

Cell adhesion to the extracellular matrix proteins occurs through interactions with integrins that bind to Arg-Gly-Asp (RGD) tripeptides, and syndecan-4, which recognizes the heparin-binding domain of other proteins. Both receptors trigger signaling pathways, including ... View more