The Multibiome: The Intestinal Ecosystem's Influence on Immune Homeostasis, Health, and Disease

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Filyk, Heather A; Osborne, Lisa C;
  • Publisher: Elsevier
  • Journal: EBioMedicine,volume 13,pages46-54 (issn: 2352-3964, eissn: 2352-3964)
  • Publisher copyright policies & self-archiving
  • Related identifiers: doi: 10.1016/j.ebiom.2016.10.007, pmc: PMC5264270
  • Subject: GF, germ-free | Helminth immunotherapy | Mucosal immunology | MS, multiple sclerosis | EBV, Epstein-Barr virus | Medicine | Microbiome | Autoimmune disease | Inflammatory bowel disease | MNV, murine norovirus | CID, chronic inflammatory disease | SFB, Segmented Filamentous Bacteria | R | IBD, inflammatory bowel disease | Review | EAE, experimental autoimmune encephalomyelitis | EE, environmental enteropathy | TSO, Trichuris suis ova | DSS, dextran sodium sulfate | HuNoV, Human Norovirus

Mammalian evolution has occurred in the presence of mutualistic, commensal, and pathogenic micro- and macro-organisms for millennia. The presence of these organisms during mammalian evolution has allowed for intimate crosstalk between these colonizing species and the ho... View more
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