Epigenetic Modulation with HDAC Inhibitor CG200745 InducesAnti-Proliferation in Non-Small Cell Lung Cancer Cells

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Chun, Sung-Min; Lee, Ji-Young; Choi, Jene; Lee, Je-Hwan; Hwang, Jung Jin; Kim, Chung-Soo; Suh, Young-Ah; Jang, Se Jin;
(2015)

Histone modification plays a pivotal role on gene regulation, as regarded as global epigenetic markers, especially in tumor related genes. Hence, chemical approaches targeting histone- modifying enzymes have emerged onto the main stage of anticancer drug discovery. Here... View more
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