Antimicrobial potential of Eucalyptus globulus against biofilms of Staphylococcus aureus isolated from bovine mastitis
Gomes, F. I.
Ferreira, Isabel C. F. R.
Staphylococcus aureus are among the most common species isolated
from bovine mastitis. The pathogenesis of this bacterium is facilitated by a
number of virulence factors, including the ability to adhere to abiotic
surfaces and/or host tissues often leading to biofilms' formation. From the
clinical perspective, the most important feature of Staphytococcus
species' biofilms is their high tolerance to the conventional antimicrobial
therapy. So, the increasing number of bovine mastitis and the higher
levels of Staphylococcus species resistance to traditional antimicrobial
agents are considered an important alert for the necessity to focus the
future research on identification and development of new strategies to
combat S. aureus mastitis. RecenUy, the interest in natural alternatives
based on plant extracts has been rising. In add~ion to their health
benefits, their antimicrobial potential has been increasingly reported.
Taking this into consideration, the evaluation of hydromethanolic extracts
of E. globulus against S. aureus biofilms was tested and compared with
penicillin, one of the antibiotics most often used in the treatment of cattle
infections. All mastitis' isolates tested were good-biofilm producers. As
expected penicillin has demonstrated poor activity against S. aureus
biofilms (<1 log reduction). However, E. globulus Labill was bactericidal,
promoting a biofilm cell reduction of 2-3 log. Therefore, the present work
showed the potential antimicrobial activity of E. g/obulus against S.
aureus from bovine mastitis, namely in biofilm mode of growth and drew
attention to its promising use as an alternative to penicillin.
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