Non-Invasive Mapping of the Gastrointestinal Microbiota Identifies Children with Inflammatory Bowel Disease

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Papa, Eliseo; Smillie, Christopher; Weber, Sarah; Preheim, Sarah P.; Gevers, Dirk; Giannoukos, Georgia; Ciulla, Dawn; Tabbaa, Diana; Ingram, Jay; Schauer, David B.; Ward, Doyle V.; Alm, Eric J.; Docktor, Michael Jason; Korzenik, Joshua; Xavier, Ramnik; Bousvaros, Athos;
  • Publisher: Public Library of Science
  • Journal: PLoS ONE,volume 7,issue 6 (issn: 1932-6203, eissn: 1932-6203)
  • Publisher copyright policies & self-archiving
  • Related identifiers: pmc: PMC3387146, doi: 10.1371/journal.pone.0039242
  • Subject: Computational Biology | Biology | Diagnostic Medicine | Test Evaluation | Research Article | Gastroenterology and Hepatology | Microbiology | Medicine | Microbial Ecology | Inflammatory Bowel Disease | Q | Ecology | R | Metagenomics | Pediatrics | Science | Genomics | Pediatric Gastroenterology
    mesheuropmc: digestive system diseases

Background: Pediatric inflammatory bowel disease (IBD) is challenging to diagnose because of the non-specificity of symptoms; an unequivocal diagnosis can only be made using colonoscopy, which clinicians are reluctant to recommend for children. Diagnosis of pediatric IB... View more
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