The effects of exogenous lipid on THP-1 cells: an in vitro model of airway aspiration?

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Hayman, Yvette A.; Sadofsky, Laura R.; Williamson, James D.; Hart, Simon P.; Morice, Alyn H.;

Chronic inflammatory diseases of the airways are associated with gastro-oesophageal reflux (GOR) and aspiration events. The observation of lipid-laden macrophages (LLMs) within the airway may indicate aspiration secondary to GOR. The proposed mechanism, that lipid dropl... View more
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