Biosynthesis of the antimicrobial cyclic lipopeptides nunamycin and nunapeptin by Pseudomonas fluorescens strain In5 is regulated by the LuxR-type transcriptional regulator NunF

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Hennessy, Rosanna C.; Phippen, Christopher B. W.; Nielsen, Kristian F.; Olsson, Stefan; Stougaard, Peter;
(2017)
  • Publisher: John Wiley and Sons Inc.
  • Journal: volume 6,issue 6issn: 2045-8827, eissn: 2045-8827
  • Publisher copyright policies & self-archiving
  • Related identifiers: doi: 10.1002/mbo3.516, pmc: PMC5727362
  • Subject: Pseudomonas | Bacterial-fungal interactions | /dk/atira/pure/researchoutput/pubmedpublicationtype/D016428 | /dk/atira/pure/researchoutput/pubmedpublicationtype/D013485 | bacterial–fungal interactions | Secondary metabolism | Original Research | Journal Article | Antimicrobial activity | Nonribosomal peptides | LuxR regulation | Research Support, Non-U.S. Gov't

Abstract Nunamycin and nunapeptin are two antimicrobial cyclic lipopeptides (CLPs) produced by Pseudomonas fluorescens In5 and synthesized by nonribosomal synthetases (NRPS) located on two gene clusters designated the nun–nup regulon. Organization of the regulon is simi... View more
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