Reanalyze unassigned reads in Sanger based metagenomic data using conserved gene adjacency

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Hsu Ming-Tsung; Su Chien-Hao; Weng Francis C; Wang Tse-Yi; Tsai Huai-Kuang; Wang Daryi;

<p>Abstract</p> <p>Background</p> <p>Investigation of metagenomes provides greater insight into uncultured microbial communities. The improvement in sequencing technology, which yields a large amount of sequence data, has led to major breakthroughs in the field. However... View more
  • References (53)
    53 references, page 1 of 6

    1. Vieites JM, Guazzaroni ME, Beloqui A, Golyshin PN, Ferrer M: Metagenomics approaches in systems microbiology. FEMS Microbiol Rev 2009, 33(1):236-255.

    2. Hugenholtz P, Tyson GW: Microbiology: Metagenomics. Nature 2008, 455(7212):481-483.

    3. Pignatelli M, Aparicio G, Blanquer I, Hernandez V, Moya A, Tamames J: Metagenomics reveals our incomplete knowledge of global diversity. Bioinformatics 2008, 24(18):2124-2125.

    4. Tringe SG, Rubin EM: Metagenomics: DNA sequencing of environmental samples. Nat Rev Genet 2005, 6(11):805-814.

    5. Biddle JF, Fitz-Gibbon S, Schuster SC, Brenchley JE, House CH: Metagenomic signatures of the Peru Margin subseafloor biosphere show a genetically distinct environment. Proceedings of the National Academy of Sciences 2008, 105(30):10583-10588.

    6. Hooper SD, Raes J, Foerstner KU, Harrington ED, Dalevi D, Bork P: A Molecular Study of Microbe Transfer between Distant Environments. PLoS ONE 2008, 3(7):e2607.

    7. Turnbaugh PJ, Ley RE, Hamady M, Fraser-Liggett CM, Knight R, Gordon JI: The Human Microbiome Project. Nature 2007, 449(7164):804-810.

    8. Fraser C, Alm EJ, Polz MF, Spratt BG, Hanage WP: The Bacterial Species Challenge: Making Sense of Genetic and Ecological Diversity. Science 2009, 323(5915):741-746.

    9. Meyer F, Paarmann D, D'Souza M, Olson R, Glass E, Kubal M, Paczian T, Rodriguez A, Stevens R, Wilke A, Wilkening J, Edwards R: The metagenomics RAST server - a public resource for the automatic phylogenetic and functional analysis of metagenomes. BMC Bioinformatics 2008, 9(1):386.

    10. Valdivia-Granda W: The next meta-challenge for Bioinformatics. Bioinformation 2008, 2(8):358-362.

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