Modulatory effects of cAMP and PKC activation on gap junctional intercellular communication among thymic epithelial cells

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Nihei, Oscar K; Fonseca, Paula C; Rubim, Nara M; Bonavita, Andre G; Lyra, Jurandy SPO; Neves-dos-Santos, Sandra; Campos de Carvalho, Antonio C; Spray, David C; Savino, Wilson; Alves, Luiz A;
(2010)
  • Publisher: Springer Nature
  • Journal: BMC Cell Biology,volume 11,pages3-3 (issn: 1471-2121, eissn: 1471-2121)
  • Related identifiers: doi: 10.1186/1471-2121-11-3, pmc: PMC2823718
  • Subject: Research article | Cell Biology

Background We investigated the effects of the signaling molecules, cyclic AMP (cAMP) and protein-kinase C (PKC), on gap junctional intercellular communication (GJIC) between thymic epithelial cells (TEC). Results Treatment with 8-Br-cAMP, a cAMP analog; or forskolin, wh... View more
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