Low Levels of IgG Recognizing the α-1-Antitrypsin Peptide and Its Association with Taiwanese Women with Primary Sjögren’s Syndrome

Article English OPEN
Chang, Yu-Sheng ; Pan, Chih-Hong ; Chang, Che-Chang ; Tsai, Kai-Leun ; Chou, Han-Wen ; Chen, Jin-Hua ; Lin, Sheng-Hong ; Lu, Yi-Ying ; Tai, Chih-Chun ; Lin, Yi-Fang ; Lin, Ching-Yu (2017)
  • Publisher: MDPI
  • Journal: International Journal of Molecular Sciences, volume 18, issue 12 (issn: 1422-0067, eissn: 1422-0067)
  • Related identifiers: pmc: PMC5751349, doi: 10.3390/ijms18122750
  • Subject: Chemistry | α-1-antitrypsin | primary Sjögren’s syndrome | inhibitor | QD1-999 | autoantibody isotypes | serum | 4-hydroxy-2-nonenal | Biology (General) | Article | QH301-705.5

The aim of this study was to examine oxidative stress and low level of α-1-antitrypsin (A1AT) in primary Sjögren’s syndrome (pSS), and evaluate the associated autoreactivity against unmodified and their 4-hydroxy-2-nonenal (HNE)-modified peptides with pSS. Two different... View more
Share - Bookmark