Pathophysiology, risk factors, and screening methods for prediabetes in women with polycystic ovary syndrome

Review, Article English OPEN
Gourgari E; Spanakis E; Dobs AS;
(2016)
  • Publisher: Dove Medical Press
  • Journal: International Journal of Women's Health,volume 8,pages381-387 (issn: 1179-1411, eissn: 1179-1411)
  • Publisher copyright policies & self-archiving
  • Related identifiers: doi: 10.2147/IJWH.S104825, pmc: PMC4986967
  • Subject: PCOS | hyperandrogenism | IR | PCOS prediabetes insulin resistance irregular menses | OGTT | RG1-991 | International Journal of Women's Health | anovulation | Review | Gynecology and obstetrics | insulin resistance | obesity | BMI
    mesheuropmc: endocrine system diseases

Evgenia Gourgari,1 Elias Spanakis,2 Adrian Sandra Dobs3 1Division of Pediatric Endocrinology, Georgetown University School of Medicine, Washington, DC, 2Division of Endocrinology, University of Maryland School of Medicine, 3Department of Endocrinology, Johns Hopkins Un... View more
  • References (61)
    61 references, page 1 of 7

    1. Legro RS, Arslanian SA, Ehrmann DA, et al. Diagnosis and treatment of polycystic ovary syndrome: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2013;98(12):4565-4592.

    2. Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome. Fertil Steril. 2004; 81(1):19-25.

    3. Diamanti-Kandarakis E, Dunaif A. Insulin resistance and the polycystic ovary syndrome revisited: an update on mechanisms and implications. Endocr Rev. 2012;33(6):981-1030.

    4. Lim SS, Davies MJ, Norman RJ, Moran LJ. Overweight, obesity and central obesity in women with polycystic ovary syndrome: a systematic review and meta-analysis. Hum Reprod Update. 2012;18(6): 618-637.

    5. Legro RS. Obesity and PCOS: implications for diagnosis and treatment. Semin Reprod Med. 2012;30(6):496-506.

    6. Yildiz BO, Knochenhauer ES, Azziz R. Impact of obesity on the risk for polycystic ovary syndrome. J Clin Endocrinol Metab. 2008;93(1): 162-168.

    7. Liang SJ, Hsu CS, Tzeng CR, Chen CH, Hsu MI. Clinical and biochemical presentation of polycystic ovary syndrome in women between the ages of 20 and 40. Hum Reprod. 2011;26(12):3443-3449.

    8. Legro RS, Kunselman AR, Dodson WC, Dunaif A. Prevalence and predictors of risk for type 2 diabetes mellitus and impaired glucose tolerance in polycystic ovary syndrome: a prospective, controlled study in 254 affected women. J Clin Endocrinol Metab. 1999;84(1):165-169.

    9. Luque-Ramirez M, Alpanes M, Escobar-Morreale HF. The determinants of insulin sensitivity, beta-cell function, and glucose tolerance are different in patients with polycystic ovary syndrome than in women who do not have hyperandrogenism. Fertil Steril. 2010;94(6): 2214-2221.

    10. Mani H, Levy MJ, Davies MJ, et al. Diabetes and cardiovascular events in women with polycystic ovary syndrome: a 20-year retrospective cohort study. Clin Endocrinol (Oxf). 2013;78(6):926-934.

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