Protection against systemic candidiasis in mice immunized with secreted aspartic proteinase 2

Article, Other literature type English OPEN
Vilanova, Manuel; Teixeira, Luzia; Caramalho, Íris; Torrado, Egídio; Marques, Andreia; Madureira, Pedro; Ribeiro, Adília; Ferreira, Paula; Gama, Miguel; Demengeot, Jocelyne;

Secreted aspartic proteinases (Sap) have been described as virulence factors implicated in the mechanisms of host colonization by the yeast Candida albicans in different types of candidiasis. Intraperitoneal inoculation of C. albicans into BALB/c mice rapidly leads to s... View more
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