High-protein intake during weight loss therapy eliminates the weight loss-induced improvement in insulin action in obese postmenopausal women

Article, Other literature type English OPEN
Smith, Gordon I. ; Yoshino, Jun ; Kelly, Shannon C. ; Reeds, Dominic N. ; Okunade, Adewole ; Patterson, Bruce W. ; Klein, Samuel ; Mittendorfer, Bettina (2016)
  • Publisher: Elsevier BV
  • Journal: Cell Reports, volume 17, issue 3, pages 849-861 (issn: 2211-1247)
  • Related identifiers: pmc: PMC5113728, doi: 10.1016/j.celrep.2016.09.047
  • Subject: high protein diet | insulin sensitivity | calorie restriction | protein | amino acids | weight loss | skeletal muscle | insulin resistance | Biology (General) | Article | QH301-705.5

High-protein (HP) intake during weight loss (WL) therapy is often recommended because it reduces the loss of lean tissue mass. However, HP intake could have adverse effects on metabolic function, because protein ingestion reduces postprandial insulin sensitivity. In thi... View more
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