Resistance to diet-induced obesity and associated metabolic perturbations in haploinsufficient monocarboxylate transporter 1 mice

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Sylvain Lengacher; Touria Nehiri-Sitayeb; Nadia Steiner; Lionel Carneiro; Céline Favrod; Frédéric Preitner; Bernard Thorens; Jean-Christophe Stehle; Laure Dix; François Pralong; Pierre J Magistretti; Luc Pellerin;

The monocarboxylate transporter 1 (MCT1 or SLC16A1) is a carrier of short-chain fatty acids, ketone bodies, and lactate in several tissues. Genetically modified C57BL/6J mice were produced by targeted disruption of the mct1 gene in order to understand the role of this t... View more
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