Resistance to Diet-Induced Obesity and Associated Metabolic Perturbations in Haploinsufficient Monocarboxylate Transporter 1 Mice
Magistretti, Pierre J.
- Publisher: Public Library of Science
(issn: 1932-6203, eissn: 1932-6203)
Q | R | Research Article | Science | Medicine
The monocarboxylate transporter 1 (MCT1 or SLC16A1) is a carrier of short-chain fatty acids, ketone bodies, and lactate in several tissues. Genetically modified C57BL/6J mice were produced by targeted disruption of the mct1 gene in order to understand the role of this t...