The Antibacterial Cell Division Inhibitor PC190723 Is an FtsZ Polymer-stabilizing Agent That Induces Filament Assembly and Condensation*

Article, Other literature type English OPEN
Andreu, José Manuel; Schaffner-Barbero, Claudia; Huecas, Sonia; Alonso, Dulce; López-Rodríguez, María L.; Ruiz-Avila, Laura B.; Núñez-Ramírez, Rafael; Llorca, Óscar; Martín-Galiano, Antonio J.;
(2010)

Cell division protein FtsZ can form single-stranded filaments with a cooperative behavior by self-switching assembly. Subsequent condensation and bending of FtsZ filaments are important for the formation and constriction of the cytokinetic ring. PC190723 is an effective... View more
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