Caspase-4 disaggregates lipopolysaccharide micelles via LPS-CARD interaction

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An, Jinsu; Kim, Seong Ho; Hwang, Dohyeon; Lee, Kyung Eun; Kim, Min Jung; Yang, Eun Gyeong; Kim, So Yeon; Chung, Hak Suk;

Abstract Lipopolysaccharides (LPS) are a major component of the outer membrane of Gram-negative bacteria and are pathogen-associated molecular patterns recognized by the TLR4/MD2 complex that induces an inflammatory response. Recently, the cytosolic receptors caspase-4/... View more
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