Increased colon cancer risk after severe Salmonella infection

Article English OPEN
Mughini-Gras, Lapo ; Schaapveld, Michael ; Kramers, Jolanda ; Mooij, Sofie ; Neefjes-Borst, E. Andra ; van Pelt, Wilfrid ; Neefjes, Jacques (2018)
  • Publisher: Public Library of Science
  • Journal: PLoS ONE, volume 13, issue 1, page e0189721 (issn: 1932-6203, eissn: 1932-6203)
  • Related identifiers: doi: 10.1371/journal.pone.0189721, pmc: PMC5771566
  • Subject: Microbial Pathogens | Digestive System | Research Article | Gastrointestinal Tract | Diagnostic Medicine | Bacteria | Anatomy | Infectious Diseases | Pathology and Laboratory Medicine | Oncology | Salmonella | Genetics | Pathogens | Cancer Detection and Diagnosis | Genetic Predisposition | Cancers and Neoplasms | Salmonella Typhimurium | Colorectal Cancer | Biology and Life Sciences | Genetics of Disease | Salmonellosis | Gastroenterology and Hepatology | Microbiology | Medicine | Bacterial Pathogens | Inflammatory Bowel Disease | Bacterial Diseases | Q | Medical Microbiology | R | Science | Organisms | Enterobacteriaceae | Colon | Medicine and Health Sciences
    mesheuropmc: digestive system diseases

Background Colon cancer constitutes one of the most frequent malignancies. Previous studies showed that Salmonella manipulates host cell signaling pathways and that Salmonella Typhimurium infection facilitates colon cancer development in genetically predisposed mice. Th... View more
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