Increased colon cancer risk after severe Salmonella infection

Article English OPEN
Mughini-Gras, Lapo; Schaapveld, Michael; Kramers, Jolanda; Mooij, Sofie; Neefjes-Borst, E Andra; Pelt, Wilfrid van; Neefjes, Jacques;
(2018)
  • Publisher: Public Library of Science
  • Journal: PLOS ONE,volume 13,issue 1,pagee0189721 (issn: 1932-6203, eissn: 1932-6203)
  • Publisher copyright policies & self-archiving
  • Related identifiers: doi: 10.1371/journal.pone.0189721, pmc: PMC5771566
  • Subject: Retrospective Studies | Colonic Neoplasms | Digestive System | Bacteria | Infectious Diseases | Young Adult | Registries | Research Support, Non-U.S. Gov't | Oncology | Genetic Predisposition | Colonic Neoplasms/complications | Animals | Female | Risk Factors | Colorectal Cancer | Biology and Life Sciences | Genetics of Disease | Salmonellosis | Gastroenterology and Hepatology | Inflammatory Bowel Disease | Bacterial Diseases | Science | Organisms | Adult | Male | Microbial Pathogens | Research Article | Gastrointestinal Tract | Diagnostic Medicine | Anatomy | Pathology and Laboratory Medicine | Mice | a_open_article_in_open_journal | Salmonella | Genetics | Salmonella Infections | Pathogens | Cancer Detection and Diagnosis | Cancers and Neoplasms | Salmonella Typhimurium | Aged | Microbiology | Medicine | Middle Aged | Bacterial Pathogens | Q | Medical Microbiology | R | Enterobacteriaceae | Colon | Journal Article | Medicine and Health Sciences | Humans | Salmonella Infections/complications
    mesheuropmc: digestive system diseases

BACKGROUND: Colon cancer constitutes one of the most frequent malignancies. Previous studies showed that Salmonella manipulates host cell signaling pathways and that Salmonella Typhimurium infection facilitates colon cancer development in genetically predisposed mice. T... View more
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