Insulin Action in Brain Regulates Systemic Metabolism and Brain Function

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Kleinridders, André; Ferris, Heather A.; Cai, Weikang; Kahn, C. Ronald;

Insulin receptors, as well as IGF-1 receptors and their postreceptor signaling partners, are distributed throughout the brain. Insulin acts on these receptors to modulate peripheral metabolism, including regulation of appetite, reproductive function, body temperature, w... View more