Amphiregulin mediates hCG-induced StAR expression and progesterone production in human granulosa cells

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Fang, Lanlan ; Yu, Yiping ; Zhang, Ruizhe ; He, Jingyan ; Sun, Ying-Pu (2016)
  • Publisher: Nature Publishing Group
  • Journal: Scientific Reports, volume 6 (issn: 2045-2322, eissn: 2045-2322)
  • Related identifiers: doi: 10.1038/srep24917, pmc: PMC4845069
  • Subject: Article
    mesheuropmc: endocrine system | urogenital system

Progesterone plays critical roles in maintaining a successful pregnancy at the early embryonic stage. Human chorionic gonadotropin (hCG) rapidly induces amphiregulin (AREG) expression. However, it remains unknown whether AREG mediates hCG-induced progesterone production... View more
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