Notch and PKC Are Involved in Formation of the Lateral Region of the Dorso-Ventral Axis in Drosophila Embryos

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Tremmel, Daniel M.; Resad, Sedat; Little, Christopher J.; Wesley, Cedric S.;
  • Publisher: Public Library of Science
  • Journal: PLoS ONE,volume 8,issue 7 (eissn: 1932-6203)
  • Related identifiers: pmc: PMC3701627, doi: 10.1371/journal.pone.0067789
  • Subject: Computational Biology | Animal Models | Research Article | Biology | Signaling | Molecular Cell Biology | Signal Transduction | Developmental Biology | Signaling Networks | Drosophila Melanogaster | Signaling in Selected Disciplines | Molecular Development | Model Organisms | Developmental Signaling
    mesheuropmc: animal structures

The Notch gene encodes an evolutionarily conserved cell surface receptor that generates regulatory signals based on interactions between neighboring cells. In Drosophila embryos it is normally expressed at a low level due to strong negative regulation. When this negativ... View more
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