Evidence for STAT4 as a common autoimmune gene: rs7574865 is associated with colonic Crohn's disease and early disease onset.
Jürgen Glas; Julia Seiderer; Melinda Nagy; Christoph Fries; Florian Beigel; Maria Weidinger; Simone Pfennig; Wolfram Klein; Jörg T Epplen; Peter Lohse; Matthias Folwaczny; Burkhard Göke; Thomas Ochsenkühn; Julia Diegelmann; Bertram Müller-Myhsok; Darina Roeske; Stephan Brand;
Subject: Research Article | Medicine | Immunology/Genetics of the Immune System | Genetics and Genomics/Genetics of the Immune System | Q | Immunology/Autoimmunity | Medizin | R | Genetics and Genomics/Genetics of Disease | Science | Gastroenterology and Hepatology/Inflammatory Bowel Disease
mesheuropmc: skin and connective tissue diseases
BACKGROUND: Recent studies demonstrated an association of STAT4 variants with systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA), indicating that multiple autoimmune diseases share common susceptibility genes. We therefore investigated the influence of STA... View more