Induction of Apoptosis in Human Multiple Myeloma Cell Lines by Ebselen via Enhancing the Endogenous Reactive Oxygen Species Production

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Zhang, Liang; Zhou, Liwei; Du, Jia; Li, Mengxia; Qian, Chengyuan; Cheng, Yi; Peng, Yang; Xie, Jiayin; Wang, Dong;
  • Publisher: Hindawi Publishing Corporation
  • Journal: BioMed Research International,volume 2,014 (issn: 2314-6133, eissn: 2314-6141)
  • Related identifiers: pmc: PMC3921973, doi: 10.1155/2014/696107
  • Subject: R | Research Article | Medicine | Article Subject

Ebselen a selenoorganic compound showing glutathione peroxidase like activity is an anti-inflammatory and antioxidative agent. Its cytoprotective activity has been investigated in recent years. However, experimental evidence also shows that ebselen causes cell death in ... View more
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