Identification of thyroid hormone receptor binding sites and target genes using ChIP-on-chip in developing mouse cerebellum.

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Dong, Hongyan; Yauk, Carole L.; Rowan-Carroll, Andrea; You, Seo-Hee; Zoeller, R. Thomas; Lambert, Iain; Wade, Michael G.;
(2009)
  • Publisher: Public Library of Science (PLoS)
  • Journal: PLoS ONE,volume 4,issue 2 (issn: 1932-6203, eissn: 1932-6203)
  • Publisher copyright policies & self-archiving
  • Related identifiers: doi: 10.1371/journal.pone.0004610, pmc: PMC2643481
  • Subject: Developmental Biology/Neurodevelopment | Research Article | Neuroscience/Neurodevelopment | Diabetes and Endocrinology/Endocrinology | Diabetes and Endocrinology/Thyroid | Medicine | Neuroscience/Cognitive Neuroscience | Diabetes and Endocrinology/Neuroendocrinology and Pituitary | Cell Biology/Gene Expression | Q | R | Science | Cell Biology/Developmental Molecular Mechanisms | Developmental Biology/Molecular Development

Thyroid hormone (TH) is critical to normal brain development, but the mechanisms operating in this process are poorly understood. We used chromatin immunoprecipitation to enrich regions of DNA bound to thyroid receptor beta (TRbeta) of mouse cerebellum sampled on post n... View more
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