Quantification of ultraviolet radiation-induced DNA damage in the urine of Swedish adults and children following exposure to sunlight.

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Liljendahl, Tove Sandberg ; Kotova, Natalia ; Segerback, Dan (2012)
  • Journal: volume 17, issue 7, pages 634-641 (issn: 1354-750X, eissn: 1366-5804)
  • Related identifiers: doi: 10.3109/1354750X.2012.709881
  • Subject: Ultraviolet radiation | Thymine dimer | 32P-postlabelling | Sunlight | Urine | Children | DNA damage | Human
    mesheuropmc: integumentary system

DNA damage following exposure to ultraviolet radiation (UVR) is important in skin cancer development. The predominant photoproduct, cyclobutane thymine dimer (T=T), is repaired and excreted in the urine, where it provides a biomarker of exposure. To quantify urinary ... View more
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