Increased p53 immunopositivity in anaplastic medulloblastoma and supratentorial PNET is not caused by JC virus

Article English OPEN
Eberhart, Charles G ; Chaudhry, Aneeka ; Daniel, Richard W ; Khaki, Leila ; Shah, Keerti V ; Gravitt, Patti E (2005)
  • Publisher: BioMed Central
  • Journal: BMC Cancer, volume 5, pages 19-19 (issn: 1471-2407, eissn: 1471-2407)
  • Related identifiers: pmc: PMC554768, doi: 10.1186/1471-2407-5-19
  • Subject: Genetics | Research Article | RC254-282 | Cancer Research | Oncology | Neoplasms. Tumors. Oncology. Including cancer and carcinogens

<p>Abstract</p> <p>Background</p> <p>p53 mutations are relatively uncommon in medulloblastoma, but abnormalities in this cell cycle pathway have been associated with anaplasia and worse clinical outcomes. We correlated p53 protein expression with pathological subtype an... View more
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