Rictor/mTORC2 signaling mediates TGFβ1-induced fibroblast activation and kidney fibrosis

Article English OPEN
Li, Jianzhong; Ren, Jiafa; Liu, Xin; Jiang, Lei; He, Weichun; Yuan, Weiping; Yang, Junwei; Dai, Chunsun;

The mammalian target of rapamycin (mTOR) was recently identified in two structurally distinct multiprotein complexes: mTORC1 and mTORC2. Previously, we found that Rictor/mTORC2 protects against cisplatin-induced acute kidney injury, but the role and mechanisms for Ricto... View more
Share - Bookmark