Enhanced drug delivery capabilities from stents coated with absorbable polymer and crystalline drug

Article, Other literature type English OPEN
Carlyle, Wenda C. ; McClain, James B. ; Tzafriri, Abraham R. ; Bailey, Lynn ; Zani, Brett G. ; Markham, Peter M. ; Stanley, James R.L. ; Edelman, Elazer R. (2012)
  • Publisher: Elsevier BV
  • Journal: Journal of Controlled Release, volume 162, issue 3, pages 561-567 (issn: 0168-3659)
  • Related identifiers: doi: 10.1016/j.jconrel.2012.07.004, pmc: PMC4637970
  • Subject: Pharmaceutical Science | Article
    mesheuropmc: equipment and supplies

Current drug eluting stent (DES) technology is not optimized with regard to the pharmacokinetics of drug delivery. A novel, absorbable-coating sirolimus-eluting stent (AC-SES) was evaluated for its capacity to deliver drug more evenly within the intimal area rather than... View more
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