Comparing ESC and iPSC—Based Models for Human Genetic Disorders
- Publisher: MDPI AG
Journal of Clinical Medicine,
(issn: 2077-0383, eissn: 2077-0383)
R | embryonic stem cells (ESCs) | induced pluripotent stem cells (iPSCs) | Review | disease modeling | Medicine
Traditionally, human disorders were studied using animal models or somatic cells taken from patients. Such studies enabled the analysis of the molecular mechanisms of numerous disorders, and led to the discovery of new treatments. Yet, these systems are limited or eve...